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10. 골?? ???rhBMP-2 LFA collagen scaffold (?)
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(4) Lidocaine
1943 ???? 뢰?그?(Nils Lfgren)?룬? 빤?Bengt Lundqvist)? ?? 미? ??취?? ?????갤? ??카?보??? ?? 측면?? 조? ???? 그?? ??카?보???? 충? ???? ???문? ??? ??취? ???????취?? ?취? 주? ? ??, ?취?? ?과?? ?? ? ? ??긴? ???린? 첨???기? ??백? 결????? ??길기 문? rhBMP-2 collagen ?백?과? ???? ?? ??? ?? ?매? ?????
?? ?? ??륩???긴? saline?? ??????? ?구조? ??거? ??리 ? 결???? 경?? ????? 경?? ? ??? 경?리?카?? ????? ?리? ??? 방? 곤?
리?카?? ?(Na channel) ?? 방??? 기?? 경과 ??근?? ?? ?? ?과 ?? ??결? ?? 방?????? ?극? ?? ???
리?켸? ?매? ??? 경? ??? ??? 첫째 ???? ?? ??? ? ?과???? ?며 째? 리??매? ??물 ??? ?? ?과???? 1:10? ???린? ?? 리?켸? ????문? 1? 30?? ? ?? ? 주?조?? ?? ?? . ?째? ?? ??? 경????? 경?? ?며 ??? ?????? ?? 면? 체?? 결?체? ?? ?? ?? ??리? 굳? ? ?? ?? ? ??? ? ??LFA collagen scaffold기?? ?? ? ?
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| Figure 10-4. 리?? ??리??, rhBMP-2, ?? 조???? ?루?? LFA collagen scaffold. |
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(5) Case presentation: rhBMP-2 LFA collagen scaffold??? MRONJ ??
| Figure10-5(1). 81???? ?? ??? ??며 ?( ?? ?? #43, #33 ??? ?? ?? )?착? ?? ????긴??? ?조골?? ? ?찰????? 겼? ???조골?? 뢰??? ?? |
| Figure 10-5(2). 구?모?? ?? 주? ??? ?며 ?조골??며 ??? ?? ???? ??면 골??? ??? ? 골?공?물 ?기? 복?? Bisphosphonate related osteonecrosis of jaws. ?근? Medication related osteonecrosis of jaws? ??? |
| Figure 10-5(3). MRONJ? ?? Bone scan ???본 결과 ?? 걸? 골괴?? 보?? ? ?? 괼? ?깨 ?리 ?? hot spot?찰?? ?며 ? steroid?물 ?기? 복??? 겼? ?며 ?? ? 측??? 겼? |
| Figure 10-5(4). #33?조골 ? ?보?? 겼? 보? 골괴?? |
| Figure10-5(5) 골?? 골? 골괴조? ?? ??방?? 골? ??? ???괴?? 보?? |
| Figure10-5(6). mandible marrow necrotic marrow?모? 거?? ?? buccal cortex lingual cortex ?공? round bur르??매?? ??과? 공?루??? ?????? ??? 공? ?루??? ??골과 ?측 ??골? ? 거?? ?면 marrow 괴?조? 벽?? 거? |
| Figure 10-5(7) rhBMP-2 LFA collagen plug?골?? ??? 모??? ????공? ?공?충?? ??? ?? rhBMP-2 LFA collagen ?? |
| Figure 10-5(8). collagen membrane rhBMP-2 LFA?coating?리? ?? ?주 |
| Figure 10-5(9). 3갤? ???? ?? 골?? healing?? ?루??? |
| Figure 10-5(10). 구?healing 모??? ? ??? ? ?remodeling과? 거?? |
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